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Ask StudybuddyAt which of the following step(s) eukaryotic gene expression can be controlled?

Question

At which of the following step(s) eukaryotic gene expression can be controlled?

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Solution

Eukaryotic gene expression can be controlled at several steps:

  1. Transcription: This is the first step in gene expression where the DNA sequence is copied into RNA. The rate of transcription can be controlled by proteins that bind to specific DNA sequences and either promote or inhibit the binding of RNA polymerase.

  2. RNA Processing: After transcription, the RNA undergoes several modifications including splicing, capping, and polyadenylation. These processes can also be regulated to control gene expression.

  3. RNA Transport: The processed RNA must be transported out of the nucleus and into the cytoplasm where it can be translated into protein. This transport can also be regulated.

  4. Translation: The process of translating the RNA sequence into a protein sequence can also be regulated. This can be done by controlling the availability of the translation machinery or by modifying the RNA sequence.

  5. Post-Translational Modifications: After the protein is made, it can be further modified by processes such as phosphorylation, acetylation, or ubiquitination. These modifications can affect the protein's activity, stability, or location in the cell, and thus can also regulate gene expression.

  6. mRNA Degradation: The stability of the mRNA can also be a point of control. Some mRNAs are very stable and last for hours, while others are rapidly degraded.

  7. Protein Degradation: Similarly, the stability of the protein product can also be a point of control. Some proteins are very stable and last for days, while others are rapidly degraded.

So, eukaryotic gene expression can be controlled at multiple steps, from the initial transcription of the gene to the final degradation of the protein product.

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