Please summarize in  at least 100 words facts that prove cigarette smoking causes cancer

Cigarette smoking is a leading cause of cancer and death from cancer. It causes cancers of the lung, esophagus, larynx, mouth, throat, kidney, bladder, liver, pancreas, stomach, cervix, colon, and rectum, as well as acute myeloid leukemia. The evidence is based on numerous epidemiological studies that have observed the high incidence of these cancers among smokers. The carcinogenic effects of smoking are attributed to the various toxins and carcinogens present in cigarette smoke, such as tar, nicotine, carbon monoxide, formaldehyde, ammonia, hydrogen cyanide, arsenic, and DDT. These substances can damage or change a cell's DNA, leading to mutations that may lead to cancer. Furthermore, smoking can weaken the immune system, making it harder for the body to kill cancer cells. When this happens, cancer cells keep growing without being stopped.