Which of the following is the plural form of the term that indicates the spread of cancer to more than one organ?

The term that indicates the spread of cancer to more than one organ is "metastasis." The plural form of "metastasis" is "metastases."

When cancer cells spread from the original (primary) site to other parts of the body, creating new tumors, this process is called metastasis. Understanding this term is crucial in oncology (the study and treatment of cancer) as it significantly impacts a patient's prognosis and treatment options. The presence of metastases often indicates an advanced stage of cancer, necessitating a more aggressive treatment approach or palliative care to manage symptoms and prolong life.

In summary, the answer to your question is "metastases."