The resting membrane potential of smooth muscle is usually Blank______ negative as that of skeletal muscle fibers.Multiple choice question.morenot as

To answer the multiple-choice question regarding the resting membrane potential of smooth muscle compared to skeletal muscle fibers, we can break it down into a couple of key points:

1. Understanding Membrane Potential: The resting membrane potential refers to the voltage difference across a cell's membrane when the cell is not actively firing an action potential. It reflects the distribution of ions across the membrane, primarily influenced by potassium ions (K+), sodium ions (Na+), and other ions.

2. Comparative Analysis:

   • Skeletal Muscle Fibers: Typically, the resting membrane potential of skeletal muscle fibers is around -90 mV. This is notably negative due to a greater permeability to potassium ions and their concentration gradient.
   • Smooth Muscle: On the other hand, the resting membrane potential of smooth muscle is generally less negative, averaging around -50 to -70 mV.

Final Answer

Given the comparative context, the correct choice would be not as negative as that of skeletal muscle fibers. Smooth muscle cells have a resting membrane potential that is less negative, indicating they have a more depolarized state compared to the tightly regulated negative potential seen in skeletal muscle fibers.