What is the target tissue of mineralocorticoids secreted from the adrenal cortex?

The target tissue of mineralocorticoids, specifically aldosterone (the primary mineralocorticoid), secreted from the adrenal cortex is primarily the distal tubules and collecting ducts of the nephrons in the kidneys.

Here's a step-by-step breakdown:

1. The adrenal cortex secretes mineralocorticoids, of which the most prominent is aldosterone.

2. Aldosterone is released into the bloodstream and travels around the body.

3. The primary target of aldosterone is the distal tubules and collecting ducts of the nephrons in the kidneys.

4. Here, aldosterone acts to increase the reabsorption of sodium ions into the bloodstream, and the excretion of potassium ions into the urine.

5. This action of aldosterone helps to increase blood volume and blood pressure, and maintain electrolyte balance in the body.