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Which neurotransmitter is primarily involved in inhibitory postsynaptic potentials (IPSPs) in the central nervous system?AAcetylcholineBDopamineCGlutamateDGABA

Question

Which neurotransmitter is primarily involved in inhibitory postsynaptic potentials (IPSPs) in the central nervous system?

  • A. Acetylcholine
  • B. Dopamine
  • C. Glutamate
  • D. GABA
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Solution

Answer

The neurotransmitter primarily involved in inhibitory postsynaptic potentials (IPSPs) in the central nervous system is D. GABA (Gamma-Aminobutyric Acid).

GABA is the main inhibitory neurotransmitter in the brain, and it functions by binding to GABA receptors, which typically opens chloride channels. When these channels open, chloride ions enter the neuron, making the inside of the neuron more negative (hyperpolarization). This process decreases the likelihood of the neuron firing an action potential, thus resulting in inhibitory effects. In contrast, acetylcholine and glutamate are primarily associated with excitatory signals, while dopamine plays various roles but is not primarily involved in inhibitory postsynaptic potentials.

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