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.Which one of the following cell types cannot utilize the TCA cycle or electron transport chain?

Question

Which one of the following cell types cannot utilize the TCA cycle or electron transport chain?

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Solution

The cell type that cannot utilize the TCA cycle (Krebs cycle) or the electron transport chain (ETC) is anaerobic organisms, particularly certain types of bacteria, as well as some cells in multicellular organisms like mature red blood cells.

Detailed Explanation:

  1. Anaerobic Organisms: These organisms do not have the necessary machinery for aerobic respiration, meaning they do not have functional mitochondria where the TCA cycle and the ETC occur. Instead, they rely on fermentation pathways to generate ATP under oxygen-limited conditions.

  2. Mature Red Blood Cells: While they derive from cells that can utilize aerobic metabolism, mature red blood cells lack mitochondria. These cells cannot perform aerobic respiration and instead utilize glycolysis to generate ATP, converting glucose to lactate in an anaerobic manner.

In summary, these types of cells rely on processes that do not involve the TCA cycle or the electron transport chain for energy production.

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