In response to action potentials arriving along the transverse tubules, the sarcoplasmic reticulum releasesQuestion 5Select one:a.H+b.Ca2+c.K+d.Na+e.ACh
Question
In response to action potentials arriving along the transverse tubules, the sarcoplasmic reticulum releases
Select one:
- a. H+
- b. Ca2+
- c. K
- d. Na+
- e. ACh
Solution
The correct answer is b. Ca2+.
Here's the step by step explanation:
-
An action potential arrives at the axon terminal of a motor neuron, which triggers the release of acetylcholine (ACh) into the synaptic cleft.
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ACh binds to receptors on the sarcolemma (the cell membrane of a muscle cell), causing an influx of Na+ ions into the muscle cell and generating an action potential that spreads across the entire sarcolemma and along the T-tubules (transverse tubules).
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The action potential traveling along the T-tubules triggers the release of Ca2+ ions from the sarcoplasmic reticulum, a specialized type of endoplasmic reticulum in muscle cells.
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The released Ca2+ ions bind to troponin, a protein found on actin filaments in muscle cells. This binding causes a conformational change in the troponin-tropomyosin complex, exposing the myosin-binding sites on actin.
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Myosin heads bind to these exposed sites on actin, forming cross-bridges. The myosin heads then undergo a power stroke, pulling the actin filaments towards the center of the sarcomere and causing muscle contraction.
-
After the power stroke, ATP binds to the myosin head, causing it to detach from actin. The ATP is then hydrolyzed, and the energy released is used to re-cock the myosin head, ready for another power stroke.
-
This process continues as long as Ca2+ ions are present. When the action potential ends, Ca2+ ions are pumped back into the sarcoplasmic reticulum, and the muscle relaxes.
So, in response to action potentials arriving along the transverse tubules, the sarcoplasmic reticulum releases Ca2+ ions.
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