This skin layer contains predominantly dead keratinocytes. epidermal layer hypodermal layer papillary layer reticular layer subcutaneous layer

The skin layer that contains predominantly dead keratinocytes is the epidermal layer. The epidermis is the outermost layer of the skin and serves as a protective barrier. It contains multiple layers of cells, primarily keratinocytes, which produce keratin, a protein that helps waterproof the skin and protect underlying tissues.

As cells in the epidermis undergo a process called keratinization, they move from the deeper layers to the surface, becoming flattened and filled with keratin, eventually dying and forming a tough, protective outer layer. This layer is constantly shedding and being replaced, which is vital for maintaining skin health and protecting against external threats like pathogens and environmental damage.

In contrast, other layers such as the hypodermal layer, papillary layer, reticular layer, and subcutaneous layer play different roles, primarily related to support, insulation, and nourishment of the skin and underlying tissues.