LDH and CYP enzymes are most likely to bind which substrates, respectively?A.NAPQI and APAPB.Lactate and APAPC.NAPQI and GSHD.Lactate and GSH
Question
LDH and CYP enzymes are most likely to bind which substrates, respectively?
A. NAPQI and APAP
B. Lactate and APAP
C. NAPQI and GSH
D. Lactate and GSH
Solution
The LDH (Lactate Dehydrogenase) enzyme is most likely to bind with Lactate as its substrate. This is because LDH's primary function is to convert lactate into pyruvate in the body.
On the other hand, CYP (Cytochrome P450) enzymes are involved in the metabolism of various molecules and chemicals within cells. One of the substrates that CYP enzymes can bind to is NAPQI (N-acetyl-p-benzoquinone imine), which is a toxic metabolite of the drug Acetaminophen (APAP).
Therefore, the correct answer is B. Lactate and APAP.
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