addition of a large concentration of certain additives to increase aqueous solubility is called

The addition of a large concentration of certain additives to increase aqueous solubility is commonly referred to as solubilization. This process involves using surfactants or other agents to enhance the solubility of poorly soluble substances in water. Surfactants work by reducing the surface tension of the solution, allowing for better dispersal and interaction of the solute with the solvent.

Solubilization is particularly important in pharmaceuticals, where it is necessary to improve the bioavailability of drugs that are poorly soluble in aqueous environments. This technique can involve various methods, such as micelle formation, where surfactant molecules aggregate to form structures that encapsulate the solute, effectively increasing its solubility.

In summary, when a large concentration of additives is incorporated to improve the aqueous solubility of a substance, it is termed solubilization, harnessing the properties of various compounds to modify solute-solvent interactions.