An important component for LTP is the insertion of more _________________ channels to strengthen the EPSP.Group of answer choicesAMPANMDAGABAGlutamate
Question
An important component for LTP is the insertion of more _________________ channels to strengthen the EPSP.
Group of answer choices
- AMPANMDA
- GABAGlutamate
Solution
The correct answer is AMPA. Long-term potentiation (LTP) is a long-lasting enhancement in signal transmission between two neurons that results from stimulating them synchronously. It is one of several phenomena underlying synaptic plasticity, the ability of chemical synapses to change their strength. As memories are thought to be encoded by modification of synaptic strength, LTP is widely considered one of the major cellular mechanisms that underlies learning and memory. AMPA receptors are involved in this process. When LTP is induced, more AMPA receptors are inserted into the synapse, which strengthens the synaptic connection and enhances the excitatory postsynaptic potential (EPSP).
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