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Which of the intermediate molecules in Krebs cycle has more than five carbons?*1 pointα-ketoglutarateSuccinyl-CoAFumarateIsocitrate

Question

Which of the intermediate molecules in Krebs cycle has more than five carbons?

  • α-ketoglutarate
  • Succinyl-CoA
  • Fumarate
  • Isocitrate
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Solution

To determine which of the intermediate molecules in the Krebs cycle (also known as the citric acid cycle or TCA cycle) contains more than five carbons, we need to look at the structure and carbon count of each intermediate mentioned:

  1. α-ketoglutarate: This molecule has 5 carbons.
  2. Succinyl-CoA: This molecule has 4 carbons.
  3. Fumarate: This molecule has 4 carbons.
  4. Isocitrate: This molecule has 6 carbons.

Conclusion:

Among the provided options, Isocitrate is the only intermediate in the Krebs cycle that has more than five carbons, with a total of six carbons.

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