The area on the enzyme where the substrate binds is calledMultiple Choicean active site.a binding pocket.a reaction site.a catalyst site.an analog.

The area on the enzyme where the substrate binds is called the active site.

Explanation:

1. Active Site: This is the specific region of an enzyme where the substrate molecules bind. The structure and chemical environment of the active site facilitate the conversion of substrates into products.
2. Binding Pocket: Though similar to the active site, this term is less commonly used in enzymatic contexts to specifically refer to where the substrate binds.
3. Reaction Site: This term is not standard in biochemistry for describing the substrate-binding area.
4. Catalyst Site: This is not typically used to specify binding areas; catalysts can operate in various forms and sites.
5. Analog: This refers to molecules that resemble the substrate but are not the binding site itself.

Therefore, the correct answer is an active site.