When treated with ammonia, acid chlorides are converted into which of the following?Select answer from the options belowAmidesCarboxylic acidsAminesAldehydes
Question
When treated with ammonia, acid chlorides are converted into which of the following?
Select answer from the options below:
- Amides
- Carboxylic acids
- Amines
- Aldehydes
Solution
When acid chlorides are treated with ammonia (NH₃), they undergo a nucleophilic acyl substitution reaction. In this reaction, ammonia acts as a nucleophile and attacks the electrophilic carbon atom of the acid chloride, leading to the formation of an intermediate. This intermediate can then rearrange to eliminate hydrochloric acid (HCl), resulting in the formation of an amide.
Thus, the correct answer is Amides.
Explanation:
- Reactivity of Acid Chlorides: Acid chlorides are highly reactive due to the presence of the electrophilic carbonyl carbon and the good leaving group (Cl).
- Nucleophilic Attack: When ammonia is introduced, the nitrogen in ammonia has a lone pair that allows it to attack the carbonyl carbon, forming a tetrahedral intermediate.
- Dehydration: The tetrahedral intermediate collapses, leading to the elimination of HCl, which completes the formation of an amide.
Therefore, the conversion of acid chlorides with ammonia yields amides as the primary product.
Similar Questions
hich of the following reaction does not liberate NH3 نقطة واحدةOxidative deaminationTransaminationTransdeaminationAll of the above
Which of the following reagents can be used to convert CH3CH2COOH into an acid chloride?Select answer from the options belowSOCl2 acetyl chlorideAlCl3HCl
Amines function chemically as organic ____.Group of answer choicesacidsbasessaltsmore than one response is correct
Which of the following is the salt formed from the neutralisation of potassium hydroxide solution and sulphuric acid?
Basic amino acid contains which of the following in its side chain?Group of answer choicesaldehydealkanecarboxylic acidamine
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.