A thiamine (Vit B1) deficiency can lead to pyruvate dehydrogenase deficiency, which can be treated with increased fat intake.TrueFalse

The statement is False.

Explanation:

Thiamine (Vitamin B1) is essential for numerous biochemical processes, particularly for the function of the pyruvate dehydrogenase complex, which converts pyruvate into acetyl-CoA. A deficiency in thiamine can impair this process, resulting in energy metabolism issues, especially in tissues that rely on glucose for energy, such as the nervous system and muscles.

Increasing fat intake may increase energy intake, but it does not directly address the deficiency of thiamine or its role in pyruvate metabolism. For treating thiamine deficiency, the most direct and effective approach is to replenish thiamine through dietary sources or supplements, rather than focusing on macronutrient composition, such as increasing fat intake. Thus, while dietary adjustments can support overall energy needs, they do not substitute for the necessity of addressing a vitamin deficiency directly.