what is peak drug x level attained at steady state if 100mg is given intravenous injection every 6hrs. the patient ke=0.35/hr and Vd = 20L

Question

what is peak drug x level attained at steady state if 100mg is given intravenous injection every 6hrs. the patient ke=0.35/hr and Vd = 20L
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Solution 1

The question is asking for the peak drug level at steady state. This can be calculated using the formula for the peak plasma concentration at steady state (Cpss max) for intermittent intravenous infusion, which is:

Cpss max = Dose / Volume of distribution * (1 - e^(-ketau)) / (1 - e^(-ketau*n))

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