A glycosidic bond forms when a hemiacetal reacts with a(n) _____ to form an acetal.Group of answer choicesthioletheralcoholester
Question
A glycosidic bond forms when a hemiacetal reacts with a(n) _____ to form an acetal.
Group of answer choices
- thiol
- ether
- alcohol
- ester
Solution
A glycosidic bond forms when a hemiacetal reacts with an alcohol to form an acetal.
Explanation
In carbohydrate chemistry, the formation of glycocidic bonds is integral to creating oligosaccharides and polysaccharides. The reaction involves a hemiacetal, a product formed when an aldehyde or ketone reacts with an alcohol, and contains a hydroxyl group (–OH) and an ether linkage (–O–). When a hemiacetal reacts with an alcohol, the hydroxyl part of the hemiacetal can condense with the alcohol, resulting in the formation of a glycosidic bond. During this process, a molecule of water is eliminated (dehydration reaction), leading to the formation of an acetal. This acetal will have two ether functionalities, making it stable and less reactive compared to hemiacetals. Thus, in this context, the missing term is "alcohol."
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