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Why would it be more likely for cells that are already rapidly dividing to develop into cancer, than it would be for something like a neurone?

Question

Why would it be more likely for cells that are already rapidly dividing to develop into cancer, than it would be for something like a neurone?

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Solution

Cancer is essentially uncontrolled cell division. Cells that are already rapidly dividing are more prone to errors during DNA replication, which can lead to mutations. If these mutations occur in genes that control cell division (oncogenes and tumor suppressor genes), they can cause the cell to divide uncontrollably, leading to cancer.

  1. Rapid Cell Division: Cells that are already dividing rapidly, such as skin cells or cells in the digestive tract, are constantly replicating their DNA. This constant replication increases the chances of a mistake or mutation occurring in the DNA sequence.

  2. DNA Mutations: These mutations can sometimes affect genes that control cell division. If a mutation causes these genes to malfunction, it can lead to uncontrolled cell division.

  3. Oncogenes and Tumor Suppressor Genes: There are two main types of genes that control cell division - oncogenes, which promote cell division, and tumor suppressor genes, which slow down cell division. Mutations that activate oncogenes or deactivate tumor suppressor genes can lead to uncontrolled cell division and cancer.

  4. Neurons: On the other hand, neurons are cells that do not divide or regenerate. Therefore, they are less likely to develop mutations that can lead to cancer. However, it's important to note that while neurons themselves may not become cancerous, they can be affected by cancer if a tumor develops in or spreads to the brain.

In conclusion, cells that are already rapidly dividing are more likely to develop into cancer because they have more opportunities for mutations to occur that can lead to uncontrolled cell division.

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