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hich one of the following mammalian cells, is not capable of metabolising glucose to CO2 aerobically?

Question

Which one of the following mammalian cells, is not capable of metabolising glucose to CO2 aerobically?

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Solution

The mammalian cell type that is not capable of metabolizing glucose to CO2 aerobically is typically:

Red Blood Cells (RBCs)

Explanation:

  1. Lack of Mitochondria: Red blood cells do not have mitochondria, which are essential for aerobic respiration. As a result, they cannot perform oxidative phosphorylation, which is necessary for aerobic metabolism of glucose to CO2.

  2. Anaerobic Metabolism: RBCs primarily rely on anaerobic glycolysis to generate ATP from glucose, converting it to lactate instead of CO2.

In summary, while most mammalian cells can oxidize glucose to CO2 aerobically, red blood cells lack the necessary organelles to do so and instead follow anaerobic pathways for energy production.

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