How can we define more than one method in a class differentiated by method signature?

In object-oriented programming, we can define more than one method within a class with the same name but different parameters. This concept is known as method overloading. The methods will be differentiated by their method signatures, which include the method name and the type, number, or order of parameters.

Here's a step-by-step guide on how to do this:

1. Define the class: First, you need to define your class. For example, in Java, you might start with public class MyClass {.

2. Define the first method: Within the class, you can define your first method. For example, `public