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Which of the following cell types does not express MHC class I?Group of answer choiceserythrocytehepatocytelymphocytedendritic cellneutrophil

Question

Which of the following cell types does not express MHC class I?

Group of answer choices:

  • erythrocyte
  • hepatocyte
  • lymphocyte
  • dendritic cell
  • neutrophil
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Solution

The cell type that does not express MHC class I is the erythrocyte, also known as a red blood cell.

Here's a step-by-step explanation:

  1. Major Histocompatibility Complex (MHC) class I molecules are a class of proteins that are found on the surface of almost all cells in the body. They play a crucial role in the immune system by presenting peptides (small pieces of proteins) to T cells, a type of white blood cell. This helps the immune system recognize and destroy cells that are infected with viruses or other pathogens.

  2. However, erythrocytes (red blood cells) do not express MHC class I molecules. This is because erythrocytes do not have a nucleus or other organelles, and therefore do not synthesize proteins.

  3. In contrast, hepatocytes (liver cells), lymphocytes (a type of white blood cell), dendritic cells (another type of white blood cell), and neutrophils (yet another type of white blood cell) all express MHC class I molecules because they have a nucleus and other organelles, and therefore can synthesize proteins.

So, the answer to your question is erythrocyte.

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