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What are the foods and medicines that should be avoided for children with G6PD deficiency? 

Research Question

What are the foods and medicines that should be avoided for children with G6PD deficiency? 
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Academic Insights

Children with G6PD deficiency should avoid certain foods and medications to prevent hemolytic anemia triggered by oxidative stress.

Key Insights

  • Foods to Avoid:

    • Fava beans are the most well-documented food that can cause severe oxidative hemolysis in individuals with G6PD deficiency .
    • High vitamin C containing foods should also be discouraged .
  • Medications to Avoid:

    • A comprehensive list of medications to be avoided includes Acetaminophen, Acetylsalicylic acid, Chloramphenicol, Chloroquine, Colchicine, Diaminodiphenyl sulfone, Diphenhydramine, Glyburide, Isoniazid, L-Dopa, Methylene blue, Nitrofurantoin, Phenazopyridine, Primaquine, Rasburicase, Streptomycin, Sulfacetamide, Sulfanilamide, Sulfapyridine, Sulfacytine, Sulfadiazine, Sulfaguanidine, Sulfamethoxazole, Sulfisoxazole, Trimethoprim, Tripelennamine, and Vitamin K .
    • Specific antibiotics from the Fluoroquinolone class (ciprofloxacin, moxifloxacin, and norfloxacin) and anti-uremic medication like rasburicase are also contraindicated .

Conclusion

Avoiding specific foods like fava beans and high vitamin C foods, along with a comprehensive list of medications, is crucial for managing G6PD deficiency in children to prevent hemolytic anemia.

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