Does taking high dosages of biotin cause elevated liver enzymes?
Research Question
Academic Insights
High dosages of biotin do not appear to cause elevated liver enzymes based on the available research.
Key Insights
-
Biotin and Liver Enzymes in Rats:
- A study on rats fed with high-dose biotin showed increased fat oxidation and decreased hepatic triglyceride levels, but did not report elevated liver enzymes .
- Another study on laying hens supplemented with biotin did not find significant changes in liver enzyme activities, suggesting no hepatotoxic effects .
-
Biotin and Liver Health in Other Contexts:
- Biotin supplementation in hens with fatty liver hemorrhagic syndrome showed beneficial effects, indicating that biotin might help alleviate liver-related issues rather than exacerbate them .
Conclusion
Current research does not support the notion that high dosages of biotin cause elevated liver enzymes. Instead, biotin appears to have neutral or potentially beneficial effects on liver health in animal studies.
Dietary High-Dose Biotin Intake Activates Fat Oxidation and Hepatic Carnitine Palmitoyltransferase in Rat.
Effect of Low dose Isotretinoin on Lipid Profile and Liver enzymes in Acne Patients: A Cross Sectional Study
The improving effects of biotin on hepatic histopathology and related apolipoprotein mRNA expression in laying hens with fatty liver hemorrhagic syndrome
LAYING PERFORMANCE, FAT DIGESTIBILITY AND LIVER CONDITION OF LAYING HENS SUPPLEMENTED WITH VITAMIN B12 OR BIOTIN AND/ OR BILE ACIDS IN DIET
Effects of repeated high dosage of chloral hydrate and pentobarbital sodium anesthesia on hepatocellular system in rats.
Emodin induces liver injury by inhibiting the key enzymes of FADH/NADPH transport in rat liver.
Beneficial Effects of Megadoses of Biotin in Streptozotocin-induced Gestational Diabetes Mellitus in Rats – A Preliminary Study
Current knowledge on biotin nutrition in fish and research perspectives
Hypoglycemic and High Dosage Effects of Bidens pilosa in Type-1 Diabetes Mellitus
Transient Elastography for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis
Impact of high-dose corticosteroid therapy for patients with HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome.
Influences of Ethanolic Extract of Peltophorum pterocarpum Leaves and Bark on Lipid Profile, Liver and Carbohydrate Metabolizing Enzymes on Toxin-induced Wistar Rats
Scientific opinion on the substantiation of a health claim related to a combination of thiamin, riboflavin, niacin, pantothenic acid, pyridoxine, D-biotin and pumpkin seed oil and maintenance of normal hair pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
The effect of pioglitazone on weight, lipid profile and liver enzymes in type 2 diabetic patients
Proanthocyanidins Attenuation of Chronic Lead-Induced Liver Oxidative Damage in Kunming Mice via the Nrf2/ARE Pathway
Effects of Betaine-Biotin-Chromium Supplementation and Concentrate to Roughage Ratio on Nutrient Utilization Efficiency in Thai Native Cattle
Effect of oral dosage of Spirulina platensis and silver nanoparticles on glucose, lipid profile, and liver enzymes in male rats induced di-abetics by alloxan
Effects of Nelumbo nucifera Gaertn. Petal Tea Extract on Hepatotoxicity and Oxidative Stress Induced by Mancozeb in Rat Model
Related Questions
- What are the side effects of high biotin intake?
- How does biotin affect liver function?
- What are normal liver enzyme levels?
- Can biotin interact with other medications?
- What is the recommended daily dosage of biotin?
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.