The ideal molecular weight of a drug intended for percutaneous absorption is above 500. True False

Analysis of the Statement

1. Understanding the Concept: The statement addresses the ideal molecular weight of a drug for percutaneous absorption—meaning the drug's ability to penetrate the skin effectively.

2. Molecular Weight and Absorption: Generally, for drugs to effectively permeate through the skin, an optimal molecular weight range is suggested. Drugs with a molecular weight greater than 500 Da often have poor absorption due to decreased penetrative ability through the lipid-rich stratum corneum (the outermost layer of the skin).

3. Conclusion: Based on the above understanding, the statement is inaccurate.

Final Answer

False. The ideal molecular weight for effective percutaneous absorption is usually below 500 Da.