Which of the following cells are macrophages acting as cell ID tag to present antigens to cell-mediated immunity or humoral immunity?
Question
Which of the following cells are macrophages acting as cell ID tag to present antigens to cell-mediated immunity or humoral immunity?
Solution
The cells you're referring to are known as Antigen Presenting Cells (APCs). Macrophages are a type of APCs. They engulf pathogens and present antigens, which are pieces of the pathogen, on their surface. These antigens are recognized by T cells, a type of white blood cell. This interaction triggers the immune response, either cell-mediated immunity or humoral immunity.
Here are the steps:
- Macrophages engulf the pathogen in a process called phagocytosis.
- The pathogen is broken down inside the macrophage, and antigens from the pathogen are moved to the surface of the macrophage.
- The macrophage, now an Antigen Presenting Cell, presents the antigens on its surface.
- T cells recognize these antigens and bind to them. This triggers the T cells to either directly kill the infected cells (cell-mediated immunity) or stimulate B cells to produce antibodies (humoral immunity).
So, in summary, macrophages act as a 'cell ID tag' to present antigens to the immune system, triggering either a cell-mediated or humoral immune response.
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