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Which of the following cells are macrophages acting as cell ID tag to present antigens to cell-mediated immunity or humoral immunity?

Question

Which of the following cells are macrophages acting as cell ID tag to present antigens to cell-mediated immunity or humoral immunity?

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Solution

The cells you're referring to are known as Antigen Presenting Cells (APCs). Macrophages are a type of APCs. They engulf pathogens and present antigens, which are pieces of the pathogen, on their surface. These antigens are recognized by T cells, a type of white blood cell. This interaction triggers the immune response, either cell-mediated immunity or humoral immunity.

Here are the steps:

  1. Macrophages engulf the pathogen in a process called phagocytosis.
  2. The pathogen is broken down inside the macrophage, and antigens from the pathogen are moved to the surface of the macrophage.
  3. The macrophage, now an Antigen Presenting Cell, presents the antigens on its surface.
  4. T cells recognize these antigens and bind to them. This triggers the T cells to either directly kill the infected cells (cell-mediated immunity) or stimulate B cells to produce antibodies (humoral immunity).

So, in summary, macrophages act as a 'cell ID tag' to present antigens to the immune system, triggering either a cell-mediated or humoral immune response.

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