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DNA condenses into sister chromatids and the nuclear envelope breaks down in which phase of mitosis?Group of answer choicesInterphaseprophaseanaphasetelophase

Question

DNA condenses into sister chromatids and the nuclear envelope breaks down in which phase of mitosis?

Group of answer choices
Interphase
prophase
anaphase
telophase

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Solution

The phase of mitosis during which DNA condenses into sister chromatids and the nuclear envelope breaks down is called prophase. Here's a brief explanation of the process:

  1. Interphase: This phase is not part of mitosis itself but is the phase where the cell prepares for mitosis. It involves DNA replication, but no visible chromosome condensation occurs yet.

  2. Prophase: This is the first stage of mitosis. During prophase, the chromatin fibers condense into visible chromosomes, and each chromosome consists of two sister chromatids joined at the centromere. Additionally, the nuclear envelope begins to break down, allowing the spindle fibers to interact with the chromosomes.

  3. Anaphase: This is the stage where the sister chromatids are pulled apart towards opposite poles of the cell, but the condensation of DNA and breakdown of the nuclear envelope already occurred in prophase.

  4. Telophase: In this final stage of mitosis, the separated chromatids reach the poles, and the nuclear envelope reforms, leading to the formation of two nuclei.

Thus, the correct answer to your question is prophase.

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