During which phase of mitosis does the nuclear envelope re-form?

Answer

The nuclear envelope re-forms during the telophase stage of mitosis.

Explanation

Mitosis is the process by which a eukaryotic cell divides its nucleus and genetic material, resulting in two identical daughter cells. It comprises several phases: prophase, metaphase, anaphase, and telophase. During telophase, the separated sister chromatids, now individual chromosomes, begin to de-condense back into chromatin. As part of this process, the nuclear envelope—previously broken down during prophase—re-forms around each set of chromosomes. This marks the final stage of nuclear division, leading to the re-establishment of the nuclei in the daughter cells.

Additionally, cytokinesis typically follows telophase, completing the cell division process. Thus, telophase is crucial not only for the restoration of nuclear integrity but also for ensuring that each daughter cell receives an accurate copy of the genetic material necessary for future cellular function.