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The activity of this enzyme is the main determinant of the rate of CHO oxidation:Group of answer choiceshexokinasepyruvate dehydrogenaseglycogen phosphorylase

Question

The activity of this enzyme is the main determinant of the rate of CHO oxidation:

Group of answer choices:

  • hexokinase
  • pyruvate dehydrogenase
  • glycogen phosphorylase
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Solution

The main determinant of the rate of carbohydrate (CHO) oxidation is the activity of the enzyme Pyruvate Dehydrogenase.

Here's a step-by-step explanation:

  1. Carbohydrates are broken down into glucose in our body.
  2. Glucose is then converted into pyruvate through a process called glycolysis.
  3. The enzyme Pyruvate Dehydrogenase is responsible for the conversion of pyruvate into acetyl-CoA, which is a key molecule in metabolism, linking glycolysis to the citric acid cycle.
  4. This step is the rate-limiting step in carbohydrate oxidation. Therefore, the activity of Pyruvate Dehydrogenase is the main determinant of the rate of carbohydrate oxidation.

Hexokinase and glycogen phosphorylase are also involved in carbohydrate metabolism, but they are not the main determinants of the rate of carbohydrate oxidation.

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