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Which cells are the most responsible for the rejection of a transplanted organ, such as a heart?Group of answer choicesmacrophagesB cellseosinophilsT cells

Question

Which cells are the most responsible for the rejection of a transplanted organ, such as a heart?

Group of answer choices

  • macrophages
  • B cells
  • eosinophils
  • T cells
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Solution

The cells most responsible for the rejection of a transplanted organ, such as a heart, are T cells.

Here's a step-by-step explanation:

  1. When a new organ is transplanted, the immune system recognizes it as foreign. This is because the immune cells, specifically T cells, can identify proteins on the cells of the transplanted organ that are different from the proteins on the recipient's own cells.

  2. T cells are a type of white blood cell that play a key role in the immune response. They are responsible for cell-mediated immunity, which is the part of the immune system that rejects foreign tissue.

  3. Once the T cells recognize the transplanted organ as foreign, they begin to attack it. This is what leads to organ rejection.

  4. Other immune cells, such as B cells, macrophages, and eosinophils, can also play a role in organ rejection. However, T cells are generally considered the most responsible because of their role in cell-mediated immunity.

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