Is a promoter located at the upstream (5’) or downstream (3’) end of a transcription unit?Group of answer choicesupstream (5’) enddownstream (3’) endNext
Question
Solution
Understanding the Placement of Promoters
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Definition of Promoter: A promoter is a region of DNA that initiates transcription of a particular gene. It is recognized and bound by RNA polymerase and transcription factors.
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Orientation of Transcription: In molecular biology, transcription proceeds from the 5' end to the 3' end of the DNA strand. Therefore, the direction in which the RNA polymerase moves is crucial for understanding where the promoter is located.
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Location Relative to the Transcription Unit: The transcription unit comprises the gene and its regulatory sequences. Since transcription starts at the promoter, it is positioned before (upstream of) the actual coding region of the gene.
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Conclusion: Given this orientation, the promoter is located at the upstream (5') end of a transcription unit.
Final Answer
The correct answer is upstream (5') end.
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