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Which of the following resistance mechanisms describes the function of β-lactamase?efflux pumptarget mimicrydrug inactivationtarget overproduction

Question

Which of the following resistance mechanisms describes the function of β-lactamase?

  • efflux pump
  • target mimicry
  • drug inactivation
  • target overproduction
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Solution

Break Down the Problem

  1. Identify the mechanisms listed: efflux pump, target mimicry, drug inactivation, target overproduction.
  2. Determine the specific function of β-lactamase in antibiotic resistance.

Relevant Concepts

  • Efflux Pump: A mechanism used by bacteria to pump out antibiotics, decreasing their effectiveness.
  • Target Mimicry: Involves bacteria mimicking the target site of the antibiotic to evade its action.
  • Drug Inactivation: A process where bacteria produce enzymes that chemically modify or degrade antibiotics.
  • Target Overproduction: Occurs when bacteria produce more of the target site than the antibiotic can effectively bind to.

Analysis and Details

  • β-lactamase is an enzyme produced by some bacteria that provide resistance to β-lactam antibiotics such as penicillin and cephalosporins.
  • The primary role of β-lactamase is to break down the β-lactam ring found in these antibiotics, rendering them ineffective.

Verify and Summarize

Considering the definitions and functions, β-lactamase clearly fits into the mechanism of drug inactivation.

Final Answer

The correct resistance mechanism described by β-lactamase is drug inactivation.

This problem has been solved

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