Which of the following resistance mechanisms describes the function of β-lactamase?efflux pumptarget mimicrydrug inactivationtarget overproduction
Question
Which of the following resistance mechanisms describes the function of β-lactamase?
- efflux pump
- target mimicry
- drug inactivation
- target overproduction
Solution
Break Down the Problem
- Identify the mechanisms listed: efflux pump, target mimicry, drug inactivation, target overproduction.
- Determine the specific function of β-lactamase in antibiotic resistance.
Relevant Concepts
- Efflux Pump: A mechanism used by bacteria to pump out antibiotics, decreasing their effectiveness.
- Target Mimicry: Involves bacteria mimicking the target site of the antibiotic to evade its action.
- Drug Inactivation: A process where bacteria produce enzymes that chemically modify or degrade antibiotics.
- Target Overproduction: Occurs when bacteria produce more of the target site than the antibiotic can effectively bind to.
Analysis and Details
- β-lactamase is an enzyme produced by some bacteria that provide resistance to β-lactam antibiotics such as penicillin and cephalosporins.
- The primary role of β-lactamase is to break down the β-lactam ring found in these antibiotics, rendering them ineffective.
Verify and Summarize
Considering the definitions and functions, β-lactamase clearly fits into the mechanism of drug inactivation.
Final Answer
The correct resistance mechanism described by β-lactamase is drug inactivation.
Similar Questions
Methicillin resistance in Staphyloccous aureus is due to:Select one alternative:efflux pumpbeta-lactamase enzymealtered metabolic pathwaymecA gene
How does an antibiotic act as a selective agent in promoting bacterial resistance
If there is NO zone of inhibition present, the bacteria is said to be ____ to the antibiotic. susceptibleintermediately susceptibleresistant
The aerobic gram- enteric are among the microbes that commonly show resistance to antibiotics.
Which of the following antibacterial drugs targets the cell wall of bacteria?ANSWERCiprofloxacinVancomycinPolymyxin BClindamycin
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