Which of the following antibacterial drugs targets the cell wall of bacteria?ANSWERCiprofloxacinVancomycinPolymyxin BClindamycin

To determine which of the listed antibacterial drugs targets the cell wall of bacteria, we need to consider the mechanisms of action of each drug:

1. Ciprofloxacin: This drug is a fluoroquinolone that primarily inhibits bacterial DNA gyrase and topoisomerase IV, which are involved in DNA replication. It does not target the cell wall.

2. Vancomycin: Vancomycin is a glycopeptide antibiotic that specifically binds to the D-alanyl-D-alanine portion of the bacterial cell wall precursors, inhibiting cell wall synthesis. It is known to be effective mainly against Gram-positive bacteria.

3. Polymyxin B: This antibiotic works by disrupting the cell membrane of Gram-negative bacteria, but it does not specifically target the cell wall.

4. Clindamycin: This is a lincosamide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It does not target the cell wall.

Final Answer

The antibacterial drug that targets the cell wall of bacteria is Vancomycin.