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Antibiotics with the root "cillin" in their names, interfere with bacterial cell .

Question

Antibiotics with the root "cillin" in their names, interfere with bacterial cell .

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Solution

Antibiotics with the root "cillin" in their names, such as penicillin and amoxicillin, interfere with bacterial cell wall synthesis. Here's a step-by-step explanation:

  1. These antibiotics belong to a group called beta-lactam antibiotics. They contain a beta-lactam ring in their molecular structure.

  2. This beta-lactam ring is able to bind to enzymes in the bacterial cell called penicillin-binding proteins (PBPs).

  3. PBPs are responsible for the final step of the synthesis of peptidoglycan, which is a major component of the bacterial cell wall.

  4. When the beta-lactam antibiotics bind to the PBPs, they inhibit the function of these enzymes.

  5. This prevents the synthesis of peptidoglycan, leading to a weak cell wall.

  6. The bacterial cell wall provides the bacteria with structural integrity and protection. Without a fully formed cell wall, the bacteria can easily be destroyed or lysed.

  7. Therefore, by interfering with the synthesis of the bacterial cell wall, "cillin" antibiotics can effectively kill bacteria or prevent them from growing and multiplying.

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