In order for a female to have an X-linked recessive disorder, both her mother and father must have it.Group of answer choicesFalseTrue

Analysis of the Statement

In X-linked recessive disorders, the gene causing the disorder is located on the X chromosome. For females (who have two X chromosomes), the condition manifests when both X chromosomes carry the mutated gene. Therefore, let's analyze the genetic inheritance:

1. Mother's Contribution:

   • A female inherits one X chromosome from her mother.
   • If the mother has the X-linked recessive disorder, she contributes an affected X chromosome (X^a).

2. Father's Contribution:

   • A female inherits one X chromosome from her father.
   • The father, having only one X chromosome (and one Y chromosome), will either have the disorder (X^aY) or will be unaffected (XY).
   • If the father has the disorder, he contributes the affected X chromosome (X^a).

3. Possible Scenarios for Inheritance:

   • If the mother is affected (X^aX^a or X^aX), she will provide an affected X chromosome.
   • If the father is affected (X^aY), he will provide an affected X chromosome.
   • However, if the mother is a carrier (X^aX) and the father is unaffected (XY), the daughter could be a carrier but not necessarily have the disorder.

Conclusion

For a female to have an X-linked recessive disorder, it is not strictly necessary for both parents to be affected. The mother must carry at least one affected X chromosome, but the father only needs to contribute an unaffected Y for his daughter to be a carrier.

Thus, the correct answer is: False.