Binding of prokaryotes DNA dependent RNA polymerase to promoter site is inhibited by:Select one:a. Streptomycinb. Puromycinc. Rifampicind. Isoniazid
Question
Binding of prokaryotes DNA dependent RNA polymerase to promoter site is inhibited by:
Select one:
- a. Streptomycin
- b. Puromycine
- c. Rifampicin
- d. Isoniazid
Solution
The binding of prokaryotes DNA dependent RNA polymerase to the promoter site is inhibited by Rifampicin.
Here's a step-by-step explanation:
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DNA-dependent RNA polymerase is an enzyme that synthesizes RNA from a DNA template, a process known as transcription.
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The promoter site is a specific DNA sequence where RNA polymerase binds and starts transcription.
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Rifampicin is an antibiotic that inhibits DNA-dependent RNA polymerase in prokaryotes.
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It does this by binding to the beta subunit of the enzyme, which is necessary for the initiation of RNA synthesis.
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This binding prevents the RNA polymerase from attaching to the promoter site on the DNA, thus inhibiting transcription.
So, the correct answer is c. Rifampicin.
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