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Binding of prokaryotes DNA dependent RNA polymerase to promoter site is inhibited by:Select one:a. Streptomycinb. Puromycinc. Rifampicind. Isoniazid

Question

Binding of prokaryotes DNA dependent RNA polymerase to promoter site is inhibited by:

Select one:

  • a. Streptomycin
  • b. Puromycine
  • c. Rifampicin
  • d. Isoniazid
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Solution

The binding of prokaryotes DNA dependent RNA polymerase to the promoter site is inhibited by Rifampicin.

Here's a step-by-step explanation:

  1. DNA-dependent RNA polymerase is an enzyme that synthesizes RNA from a DNA template, a process known as transcription.

  2. The promoter site is a specific DNA sequence where RNA polymerase binds and starts transcription.

  3. Rifampicin is an antibiotic that inhibits DNA-dependent RNA polymerase in prokaryotes.

  4. It does this by binding to the beta subunit of the enzyme, which is necessary for the initiation of RNA synthesis.

  5. This binding prevents the RNA polymerase from attaching to the promoter site on the DNA, thus inhibiting transcription.

So, the correct answer is c. Rifampicin.

This problem has been solved

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