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Understand the role of cartilage in bone formation and growth in length of long bones.

Question

Understand the role of cartilage in bone formation and growth in length of long bones.

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Solution

Cartilage plays a crucial role in the formation and growth of long bones in the body. Here's a step-by-step explanation of how this process works:

  1. Bone Formation: The process of bone formation is known as ossification. During the early stages of fetal development, the skeleton is made up of fibrous membranes and hyaline cartilage. These tissues are soft and flexible, providing the necessary framework for the formation of bones.

  2. Role of Cartilage: The cartilage does not transform into bone. Instead, it serves as a model or a blueprint for bone formation. This process is known as endochondral ossification.

  3. Endochondral Ossification: In this process, the cartilage is gradually replaced by bone. It begins with the development of a cartilage model. The cells in the middle of this model begin to change into osteoblasts, which are bone-forming cells. These osteoblasts start to secrete bone matrix, which hardens to form bone.

  4. Growth Plates: The growth of long bones in length occurs at the epiphyseal plate (or growth plate) which is made of cartilage. This plate is found near the ends of the long bones.

  5. Bone Growth: New cartilage is produced on the side of the plate facing away from the rest of the bone, pushing the ends of the bone away and making the bone longer. At the same time, old cartilage on the side of the plate facing the rest of the bone is replaced by new bone.

  6. Completion of Growth: This process continues throughout childhood and adolescence. When growth is complete--usually in early adulthood--the cartilage in the growth plate is replaced by bone, and no more growth in length is possible.

In summary, cartilage plays a vital role in bone formation by providing a model for bone growth and facilitating the growth in length of long bones.

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