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Which of the following tools can be used for local alignment: BLAST Clustal Omega Needleman–Wunsch algorithm KEGG

Question

Which of the following tools can be used for local alignment:

  • BLAST
  • Clustal Omega
  • Needleman–Wunsch algorithm
  • KEGG
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Solution

The tools that can be used for local alignment from the list you provided are:

  1. BLAST (Basic Local Alignment Search Tool): This is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the letters of DNA sequences. It finds regions of local similarity between sequences, which can be used to infer functional and evolutionary relationships.

  2. Needleman–Wunsch algorithm: This is an algorithm used in bioinformatics to align protein or nucleotide sequences. However, it's important to note that this algorithm is typically used for global alignment, not local alignment.

Clustal Omega and KEGG are not typically used for local alignment. Clustal Omega is a multiple sequence alignment program that uses seeded guide trees and HMM profile-profile techniques to generate alignments. KEGG (Kyoto Encyclopedia of Genes and Genomes) is a database resource that integrates genomic, chemical and systemic functional information.

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