Which one of the following programs is used for finding distantly related (orremote) protein homologs?(A) BLASTN(B) BLASTX(C) PSI-BLAST(D) TBLASTX
Question
Which one of the following programs is used for finding distantly related (or remote) protein homologs?
- (A) BLASTN
- (B) BLASTX
- (C) PSI-BLAST
- (D) TBLASTX
Solution
The program used for finding distantly related (or remote) protein homologs is (C) PSI-BLAST.
Here's why:
(A) BLASTN is used for nucleotide queries against a nucleotide database. (B) BLASTX is used for translating a nucleotide query into protein and then searching it against a protein database. (C) PSI-BLAST (Position-Specific Iterated BLAST) is used for finding distant protein relatives. It uses an iterative search with a profile built from the alignments in the search results. (D) TBLASTX is used for translating a nucleotide query and database into protein and then searching them against each other.
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