T-cell precursors are made in the __________ and mature in the __________.ANSWERthymus; thymusbone marrow; bone marrowbone marrow; thymusthyroid; bone marrow

T-cell precursors are made in the bone marrow and mature in the thymus.

To elaborate, T-cells, a vital component of the adaptive immune system, originate from pluripotent stem cells in the bone marrow. After their initial formation, these precursors migrate to the thymus, an organ located in the upper chest, where they undergo a rigorous maturation process. During this time, they undergo selection processes to ensure that they can recognize specific antigens while remaining tolerant to self-antigens, preventing autoimmune reactions. This maturation in the thymus is critical for the development of fully functional T-cells capable of responding to infections and contributing to immune defense.

Final Answer

Bone marrow; thymus.