Which of the following is responsible for the formation of uric acid?Deamination reactionKreb’s cycleOrnithine cycleIonosinic pathway

Step 1: Break Down the Problem

To identify the correct answer, we need to analyze each of the given options in relation to the formation of uric acid.

Step 2: Relevant Concepts

1. Deamination Reaction: This is a process where an amino acid loses its amino group. While this does contribute to the formation of ammonia and subsequently urea, it is not directly responsible for uric acid production.

2. Kreb’s Cycle: Also known as the citric acid cycle, this pathway is involved in the conversion of carbohydrates, fats, and proteins into carbon dioxide and water, generating ATP. It does not produce uric acid.

3. Ornithine Cycle: This cycle, also known as the urea cycle, is responsible for converting ammonia into urea for excretion in urine, not uric acid.

4. Ionosinic Pathway: This pathway refers to the purine nucleotide cycle, which leads to the formation of uric acid as a waste product during the breakdown of purines like adenine and guanine.

Step 3: Analysis and Detail

Upon reviewing the functions of the pathways:

• Deamination is more associated with ammonia and urea formation.
• Kreb's cycle is primarily focused on energy production.
• Ornithine cycle primarily excretes urea, not uric acid.
• The Ionosinic pathway specifically handles the breakdown of purines leading directly to uric acid formation.

Step 4: Verify and Summarize

From the analysis above, the Ionosinic pathway is indeed responsible for the formation of uric acid through purine metabolism.

Final Answer

The correct answer is Ionosinic pathway.