The question asks about a web server specifically designed for predicting protein stability upon mutation. Here’s a breakdown of each option:

1. **FOLD-RATE**: This server focuses on the prediction of the folding rates of proteins but may not be specifically tailored for assessing stability upon mutation.

2. **iSEE**: This is typically a web tool used for various bioinformatics analyses but does not solely specialize in predicting protein stability due to mutations.

3. **ProTherm**: This database contains information on protein stability and thermal denaturation. It can provide insights into the stability of proteins but is more of a database than a predictive tool.

4. **CUPSAT**: This tool is explicitly designed for assessing the stability of proteins upon mutation. It uses statistical mechanics principles to predict how mutations affect protein stability.

### Final Answer
**CUPSAT** is the web server specifically designed for discriminating and predicting protein stability upon mutation.

Question

The question asks about a web server specifically designed for predicting protein stability upon mutation. Here’s a breakdown of each option:

1. **FOLD-RATE**: This server focuses on the prediction of the folding rates of proteins but may not be specifically tailored for assessing stability upon mutation.

2. **iSEE**: This is typically a web tool used for various bioinformatics analyses but does not solely specialize in predicting protein stability due to mutations.

3. **ProTherm**: This database contains information on protein stability and thermal denaturation. It can provide insights into the stability of proteins but is more of a database than a predictive tool.

4. **CUPSAT**: This tool is explicitly designed for assessing the stability of proteins upon mutation. It uses statistical mechanics principles to predict how mutations affect protein stability.

### Final Answer
**CUPSAT** is the web server specifically designed for discriminating and predicting protein stability upon mutation.

Knowee AI · Accepted Answer

The question asks about a web server specifically designed for predicting protein stability upon mutation. Here’s a breakdown of each option:

1. **FOLD-RATE**: This server focuses on the prediction of the folding rates of proteins but may not be specifically tailored for assessing stability upon mutation.

2. **iSEE**: This is typically a web tool used for various bioinformatics analyses but does not solely specialize in predicting protein stability due to mutations.

3. **ProTherm**: This database contains information on protein stability and thermal denaturation. It can provide insights into the stability of proteins but is more of a database than a predictive tool.

4. **CUPSAT**: This tool is explicitly designed for assessing the stability of proteins upon mutation. It uses statistical mechanics principles to predict how mutations affect protein stability.

### Final Answer
**CUPSAT** is the web server specifically designed for discriminating and predicting protein stability upon mutation.

Which of the following is a web server for discriminating and predicting the protein stability upon mutation? FOLD-RATE iSEE ProTherm CUPSAT

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