The synthetic PGE1 analog used to treat peptic ulcer disease but poses the risk of unwanted uterine contraction and abortions

The synthetic PGE1 analog used to treat peptic ulcer disease is Misoprostol. Misoprostol is a prostaglandin analog that is used to prevent gastric ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing the amount of acid that your stomach produces, protecting the stomach lining, and promoting healing of ulcers.

However, Misoprostol also has effects on the uterus and can cause contractions, which can lead to abortion. This is why it is also used in some cases for medical abortions or to induce labor. Therefore, it is contraindicated in pregnant women who are not intending to terminate their pregnancy. It's important that women of childbearing age use effective birth control while taking this medication.