When alcohol is metabolised in the liver, what redox molecule is generated is massive amounts?Group of answer choicesFADH2NAD+FADNADH

When alcohol is metabolized in the liver, the primary redox molecule that is generated in massive amounts is NADH.

Explanation

1. Alcohol Metabolism Process: Ethanol is converted to acetaldehyde by the enzyme alcohol dehydrogenase (ADH). During this process, NAD+ is reduced to NADH.

2. Further Metabolism: Acetaldehyde is then converted to acetate by the enzyme aldehyde dehydrogenase, which also requires NAD+ and produces more NADH.

3. Excess NADH Consequences: The substantial production of NADH can lead to an imbalance in the NAD+/NADH ratio, influencing various metabolic pathways and potentially leading to conditions such as alcoholic fatty liver disease.

Conclusion

In summary, the correct answer to the question is NADH. This molecule plays a crucial role during the metabolism of alcohol in the liver.