Define PSI-BLAST and PHI-BLAST algorithms. How do they extend the functionality of the basic BLAST algorithm?

Question

Define PSI-BLAST and PHI-BLAST algorithms. How do they extend the functionality of the basic BLAST algorithm?
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Solution 1

PSI-BLAST (Position-Specific Iterated BLAST) and PHI-BLAST (Pattern Hit Initiated BLAST) are two extensions of the basic BLAST (Basic Local Alignment Search Tool) algorithm, which is used in bioinformatics to compare primary biological sequence information.

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