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Do you think Picking Mottling, match Defects of tablet coating involving flaking of the coating, uneven distribution of color.

Question

Do you think Picking Mottling, match Defects of tablet coating involving flaking of the coating, uneven distribution of color.

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Solution

Yes, Picking and Mottling can be considered as defects of tablet coating.

  1. Picking: This defect occurs when the tablet coating gets removed in the drying phase of the coating process. This can happen due to the coating solution penetrating the tablet surface and causing the tablet to stick to the coating pan. When the tablet is removed from the pan, the coating can peel off, resulting in a defect known as picking.

  2. Mottling: This defect is characterized by an uneven distribution of color on the tablet surface. It can occur due to various reasons such as uneven spray pattern, improper mixing of the coating solution, or variations in tablet surface.

So, both picking and mottling are defects that involve issues with the coating of the tablet, but they are different in nature. Picking involves flaking of the coating, while mottling involves uneven color distribution.

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