What is the commonest clinical presentation of infection with Enatmoeba histolytica?

The most common clinical presentation of infection with Entamoeba histolytica is asymptomatic carriage. This means that the majority of individuals infected with this parasite do not show any symptoms.

However, when symptoms do occur, they typically present as amoebic dysentery or amoebiasis. This is characterized by abdominal pain, diarrhea (often with blood and mucus), weight loss, and fatigue. In severe cases, the parasite can invade the liver and cause amoebic liver abscesses, which can present with fever, right upper quadrant pain, and hepatomegaly (enlarged liver).

It's important to note that these symptoms can be similar to other gastrointestinal diseases, so a definitive diagnosis usually requires laboratory testing, such as a stool test or imaging studies.