n DNA replication, the Okazaki fragments are joined by(A) DNA helicase(B) DNA ligase(C) DNA polymerase(D) DNA primase

In DNA replication, the Okazaki fragments are joined by (B) DNA ligase.

Here's a step-by-step explanation:

1. DNA replication begins at specific sites called origins of replication. The two DNA strands are separated by an enzyme called DNA helicase, creating a replication fork.

2. On the leading strand, DNA polymerase synthesizes a new strand of DNA in the direction of the replication fork, continuously.

3. On the lagging strand, DNA synthesis occurs in a discontinuous manner, creating Okazaki fragments. This is because DNA polymerase can only add nucleotides in the 5' to 3' direction.

4. These Okazaki fragments are then joined together by the enzyme DNA ligase, creating a continuous DNA strand.

So, the correct answer is (B) DNA ligase.