Which of these techniques gives us molecular weight information from which we can work out a molecular formula?Group of answer choices

To determine the molecular weight information from which we can derive a molecular formula, several analytical techniques can be considered. Here are some techniques that are commonly used:

1. Mass Spectrometry (MS): This is a powerful technique that provides the mass-to-charge ratio of ions. By analyzing the mass spectrum, we can obtain information about the molecular weight of a compound, which helps in determining its molecular formula.

2. Gas Chromatography-Mass Spectrometry (GC-MS): Combining gas chromatography with mass spectrometry allows for separation and subsequent mass analysis of compounds, providing molecular weight data.

3. High-Performance Liquid Chromatography (HPLC) Coupled with Mass Spectrometry: Similar to GC-MS, HPLC can also be combined with mass spectrometry to give detailed molecular weight and structural information.

Each of these techniques provides critical molecular weight data that are essential for deducing the molecular formula of a compound. While some techniques, like nuclear magnetic resonance (NMR) spectroscopy, can provide structural information, they do not directly offer molecular weight data in a straightforward manner as mass spectrometry does. Therefore, Mass Spectrometry and its coupling with chromatographic techniques are the most reliable for determining molecular weight.