Local inhibition of which chemical would increase gastric acid secretion?• Acetylcholine• GastrinO Histamine• Somatostatin
Question
Local inhibition of which chemical would increase gastric acid secretion?
- Acetylcholine
- Gastrin
- Histamine
- Somatostatin
Solution
The chemical that, when locally inhibited, would increase gastric acid secretion is Somatostatin.
Here's the step-by-step explanation:
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Gastric acid secretion in the stomach is regulated by several hormones and neurotransmitters.
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Acetylcholine, Gastrin, and Histamine are all stimulants of gastric acid secretion. They bind to their respective receptors on the parietal cells in the stomach lining, triggering the secretion of gastric acid.
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Somatostatin, on the other hand, is an inhibitor of gastric acid secretion. It acts by binding to its receptors on the parietal cells, inhibiting the action of the stimulants and thereby reducing the secretion of gastric acid.
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Therefore, if the action of Somatostatin is locally inhibited, it would mean that there is less inhibition of the stimulants. This would result in an increase in gastric acid secretion.
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